PYOGENIC SPONDYLODISCITIS: RISK FACTORS FOR THERAPEUTIC FAILURE AND RECURRENCE

ABSTRACT Objective: Evaluate the prognostic factors associated with therapeutic failure and recurrence in pyogenic spondylodiscitis (PS). Methods: A historical cohort study was conducted a reference Brazilian hospital for locomotor system neurodevelopmental diseases. All patients PS treated between January 1999 December 2018 followed at least one year were included. defined based on clinical, laboratory, radiological criteria. Microbiological data clinical outcomes end of follow-up also collected analyzed. Results: Fifty (mean age 50.94 ± 15.84 years, men 76.00%) After twelve months follow-up, observed 24.00% (n = 12) 18.00% 09) patients. Among those who cured, residual symptoms found 50.00% (19/38). No deaths observed. multivariate analysis, prescription antibiotic therapy before culture results (p 0.0153), spinal cord compression 0.0053), sensory deficits 0.0341). Furthermore, previous nonspinal surgeries 0.0350) 0.0447). Conclusion: causes significant morbidity. The prognosis depends mainly presentation admission, especially when compression, which reinforces importance early diagnosis. Level Evidence II; Prognostic Studies.